This monoclonal antibody specifically recognizes the cleaved form of PARP1, a nuclear enzyme involved in DNA damage repair. Cleaved PARP1 fragments are common biomarkers of apoptosis, resulting from caspase activation during the apoptotic process. This antibody does not recognize full-length PARP1.
- Specifically recognizes cleaved PARP1
- Clone 4G4C8
- Host species: Mouse
- Isotype: IgG1
- Reactivity: Human, mouse, rat
- Applications: Western Blot, Immunohistochemistry, Immunofluorescence/ICC, Flow Cytometry (Intra), ELISA
- Concentration: 1000 μg/mL
- Volume: 150 μL
- Formulation: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3
- Unconjugated
- Purification method: Protein G purification
- Store at -20°C; stable for one year after shipment